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Galanthaminone
SKU
HY-I0020-10 mg
Category Reference compound
Tags Cholinesterase (ChE), Neurological Disease, Neuronal Signaling
$156 – $600
Products Details
Product Description
– Galanthaminone (Narwedin) is a competitive and reversible cholinesterase (AChE) inhibitor; is used for the treatment of mild to moderate Alzheimer’s disease and various other memory impairments.
Web ID
– HY-I0020
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C17H19NO3
References
– [1]Greenblatt HM, et al. Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 A resolution. FEBS Lett. 1999 Dec 17;463(3):321-6.|[2]Heinrich M, et al. Galanthamine from snowdrop–the development of a modern drug against Alzheimer’s disease from local Caucasian knowledge. J Ethnopharmacol. 2004 Jun;92(2-3):147-62.
CAS Number
– 510-77-0
Molecular Weight
– 285.34
Compound Purity
– 99.63
SMILES
– O=C1C=C[C@@]23CCN(C)CC4=CC=C(OC)C(O[C@@]3([H])C1)=C24
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 10 mg/mL (ultrasonic)|H2O : 0.67 mg/mL (ultrasonic)
Target
– Cholinesterase (ChE)
Isoform
– AChE
Pathway
– Neuronal Signaling
Product type
– Reference compound
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