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Gal-C4-Chol
SKU
HY-112752-Get quote
Category Reference compound
Tags Liposome, Metabolic Enzyme/Protease, Others
Products Details
Product Description
– Gal-C4-Chol is a glycosylated cholesterol derivative. Gal-C4-Chol can be used as a ligand for asialoglycoprotein receptors (ASGPR) to prepare Galactosylated (Gal) liposomes. Gal-C4-Chol can be used to prepare simple lipid-based nanoparticles[1][2][3].
Web ID
– HY-112752
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C40H69N3O7S
References
– [1]Managit C, et al. Effect of galactose density on asialoglycoprotein receptor-mediated uptake of galactosylated liposomes. J Pharm Sci. 2005 Oct;94(10):2266-75.|[2]Kawakami S, et al. Biodistribution characteristics of mannosylated, fucosylated, and galactosylated liposomes in mice. Biochim Biophys Acta. 2000 Dec 15;1524(2-3):258-65.|[3]Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811.
CAS Number
– 219850-70-1
Molecular Weight
– 736.06
SMILES
– C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(NCCCCNC(CS[C@@H]4O[C@@H]([C@@H]([C@@H]([C@H]4O)O)O)CO)=N)=O)([H])[C@@]5([H])[C@](CC3)([C@@](CC5)([H])[C@H](C)CCCC(C)C)C
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Liposome
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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