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Products Details
Product Description
– G43 is a potent, selective glucosyltransferase inhibitor, with the Kd of 3.7μM and 46.9 nM for GtfB and GtfC, respectively. G43 has antibacterial to S. mutans in vitro and in vivo, and can be used for dental caries study[1][2].
Web ID
– HY-155715
Shipping
– Room temperature
Molecular Formula
– C16H11N3O4S
References
– [1]Zhang Q, et al. Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence. Sci Rep. 2017;7(1):5974.|[2]Scaffa PMC, et al. The potential use of glycosyl-transferase inhibitors for targeted reduction of S. mutans biofilms in dental materials. Sci Rep. 2023;13(1):11889.
CAS Number
– 690693-02-8
Molecular Weight
– 341.34
SMILES
– O=C(C1=CC2=C(S1)C=CC([N+]([O-])=O)=C2)NC3=CC=CC=C3C(N)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;Glucosylceramide Synthase (GCS)
Pathway
– Anti-infection;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
