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Products Details
Product Description
– G-9791, a poyridone side chain analogue, is a potent PAK inhibitor with Ki values of 0.95 nM and 2.0 nM for PAK1 and PAK2, respectively[1].
Web ID
– HY-116917
Shipping
– Room temperature
Molecular Formula
– C26H26ClFN6O2
References
– [1]Rudolph J, et, al. Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window. J Med Chem. 2016 Jun 9;59(11):5520-41.
CAS Number
– 1926204-95-6
Molecular Weight
– 508.98
SMILES
– O=C1C(C2=CC=C(N3C=CC=C(C)C3=O)C=C2Cl)=CC4=CN=C(NC)N=C4N1CCC5(F)CN(C)C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PAK
Isoform
– PAK1;PAK2
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
