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Products Details
Product Description
– G-418 (Geneticin) is an aminoglycoside antibiotic with a structure similar to gentamicin. It is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis[1].
Web ID
– HY-108718
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H40N4O10
Citations
– Acta Pharmacol Sin. 2023 May 16.|FASEB J. 2023 Nov;37(11):e23195.|Research Square Preprint. 2023 Jul 11.|Am J Cancer Res. 2021 May 15;11(5):2062-2080.|Cancer Commun (Lond). 2022 Nov 9.|Cancer Res. 2023 Feb 6;CAN-22-3169.|Cell Death Differ. 2020 Jun;27(6):1981-1997.|Cell Death Dis. 2020 Jun 4;11(6):420.|Cell Death Dis. 2019 May 28;10(6):413.|Cell Rep. 2020 Oct 20;33(3):108287.|Cell Rep. 2021 Mar 30;34(13):108906.|Cell Rep. 2021 Sep 21;36(12):109739.|Cell Rep. 2022 Oct 25;41(4):111561.|Emerg Microbes Infect. 2023 Sep 19;2261556.|Hum Cell. 2022 Jul 6.|J Agric Food Chem. 2022 Apr 6;70(13):3989-3999.|J Biol Chem. 2023 Mar 17;104621.|J Cell Mol Med. 2023 Mar 13.|J Genet Genomics. 2021 Mar 30.|Med Oncol. 2021 Nov 10;39(1):10.|Mol Cell. 2023 Nov 20:S1097-2765(23)00914-0.|Nature. 2023 Jun;618(7966):862-870.|Oxid Med Cell Longev. 2022 Jan 28;2022:8168988.|Research Square Preprint. 2020 Jun.|Research Square Preprint. 2021 Nov.|Research Square Print. 2023 Feb 21.|Theranostics. 2022 Jan 1;12(3):1187-1203.|Transl Cancer Res. 2023 Jan 23; 12(1):150-162.
References
– [1]S Bennett, et al. Reliable method of isolating transfected clones from the LNCaP human prostatic cell line. Biotechniques. 1997 Jul;23(1):66, 68, 70.
CAS Number
– 49863-47-0
Molecular Weight
– 496.55
SMILES
– O[C@@H]([C@@H]1O[C@@]([C@@H]([C@@H](O)[C@@H]2O)N)([H])O[C@]2([H])[C@H](O)C)[C@H]([C@@H](C[C@@H]1N)N)O[C@](OC[C@](C)(O)[C@@H]3NC)([H])[C@@H]3O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial;Parasite
Isoform
– Aminoglycoside
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
