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Products Details
Product Description
– FY-56 is a highly potent and selective LSD1/KDM1A inhibitor (IC50=42 nM) and exhibits high selectivity over MAO-A/B. FY-56 induces differentiation of MOLM-13 and MV4-11 cell and has the potential for AML research[1].
Web ID
– HY-143238
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H19FN2O3
References
– [1]Chao Yang, et al. Discovery of natural product-like spirooxindole derivatives as highly potent and selective LSD1/KDM1A inhibitors for AML treatment. Bioorg Chem. 2022 Mar; 120:105596
Molecular Weight
– 390.41
SMILES
– O=C1N(C2=C(C13NCCC4=CC(O)=C(C=C43)O)C=CC=C2)CC5=C(C=CC=C5)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Demethylase
Isoform
– KDM1/LSD1
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
