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Products Details
Product Description
– FXIa-IN-7 is a selective and orally bioavailable factor XIa inhibitor with an IC50 value of 0.4 nM.
Web ID
– HY-145354
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C28H28N2O4
References
– [1]Lorthiois E, et al. Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach. J Med Chem. 2020 Aug 13;63(15):8088-8113.
CAS Number
– 2488952-56-1
Molecular Weight
– 456.53
SMILES
– O=C(C1=CC=CC2=C1N(C[C@H](C3=CC(C(C)C)=CC(C4=CC=C(OC[C@H]5N)C5=C4)=C3)O)C=C2)O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Factor Xa
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
