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Products Details
Product Description
– FXa-IN-1 is a FXa inhibitor (IC50: 3 nM, Ki: 0.7 nM) with respectable oral bioavailability and half-life in vivo. FXa-IN-1 can be used for thromboembolic disorders[1].
Web ID
– HY-10758
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C24H18F5N5O
References
– [1]Zhaozhong J Jia, et al. 1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides as potent factor Xa inhibitors. Part 3: Design, synthesis and SAR of orally bioavailable benzamidine-P4 inhibitors. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1229-34.
CAS Number
– 441328-10-5
Molecular Weight
– 487.42
SMILES
– O=C(NC1=CC=C(C(N(C)C)=N)C=C1F)C2=CC(C(F)(F)F)=NN2C3=C(F)C=C(C=CC=C4)C4=C3
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Factor Xa
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
