Products Details

Product Description

– Fuscin, a fungal metabolite, CCR5 receptor antagonist with anti-HIV effects. Fuscin is a respiration and oxidative phosphorylation inhibitor, and also a mitochondrial SH-dependent transport-linked functions inhibitor[1][2][3].

Web ID

– HY-111321

Shipping

– Room temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C15H16O5

References

– [1]K Yoganathan, et al. 10-Methoxydihydrofuscin, fuscinarin, and fuscin, novel antagonists of the human CCR5 receptor from Oidiodendron griseum. J Nat Prod. 2003 Aug;66(8):1116-7. |[2]K S Cheah. Fuscin, an inhibitor of respiration and oxidative phosphorylation in ox-neck muscle mitochondria. Biochim Biophys Acta.1972 Jul 12;275(1):1-9. |[3]P M Vignais, et al. Fuscin, an inhibitor of mitochondrial SH-dependent transport-linked functions. Biochim Biophys Acta. 1973 Dec 14;325(3):357-74.

CAS Number

– 83-85-2

Molecular Weight

– 276.28

SMILES

– O=C1C=C2C(C(C)O1)=C(O)C(C3=C2CCC(C)(C)O3)=O

Clinical Information

– No Development Reported

Research Area

– Infection; Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Bacterial;CCR;Endogenous Metabolite;HIV;Mitochondrial Metabolism

Isoform

– CCR5;HIV;Microbial Metabolite

Pathway

– Anti-infection;GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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