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Fuscin
$708 – $2,124
Products Details
Product Description
– Fuscin, a fungal metabolite, CCR5 receptor antagonist with anti-HIV effects. Fuscin is a respiration and oxidative phosphorylation inhibitor, and also a mitochondrial SH-dependent transport-linked functions inhibitor[1][2][3].
Web ID
– HY-111321
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C15H16O5
References
– [1]K Yoganathan, et al. 10-Methoxydihydrofuscin, fuscinarin, and fuscin, novel antagonists of the human CCR5 receptor from Oidiodendron griseum. J Nat Prod. 2003 Aug;66(8):1116-7. |[2]K S Cheah. Fuscin, an inhibitor of respiration and oxidative phosphorylation in ox-neck muscle mitochondria. Biochim Biophys Acta.1972 Jul 12;275(1):1-9. |[3]P M Vignais, et al. Fuscin, an inhibitor of mitochondrial SH-dependent transport-linked functions. Biochim Biophys Acta. 1973 Dec 14;325(3):357-74.
CAS Number
– 83-85-2
Molecular Weight
– 276.28
SMILES
– O=C1C=C2C(C(C)O1)=C(O)C(C3=C2CCC(C)(C)O3)=O
Clinical Information
– No Development Reported
Research Area
– Infection; Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Bacterial;CCR;Endogenous Metabolite;HIV;Mitochondrial Metabolism
Isoform
– CCR5;HIV;Microbial Metabolite
Pathway
– Anti-infection;GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Natural Products
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