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Fumarate hydratase-IN-2 (sodium salt)
$180 – $1,920
Products Details
Product Description
– Fumarate hydratase-IN-2 sodium salt (compound 3) is a cell-permeable and competitive fumarate hydratase inhibitor (Ki=4.5 μM) with nutrient-dependent cytotoxicity [1].
Web ID
– HY-100005A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H25N2NaO4
References
– [1]Takeuchi T et al. Identification of fumarate hydratase inhibitors with nutrient-dependent cytotoxicity. J Am Chem Soc. 2015 Jan 21;137(2):564-7.
CAS Number
– 2070009-45-7
Molecular Weight
– 440.47
Compound Purity
– 98.02
SMILES
– O=C(O[Na])[C@]1([C@H](CC(NC)=O)C2=O)C(N2CC(C=C3)=CC=C3C4=CC=CC=C4)=CCCC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 10.66 mg/mL (ultrasonic;warming)|H2O : 6.25 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Mitochondrial Metabolism
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
