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Products Details
Product Description
– FtsZ-IN-6 is a potent FtsZ inhibitor, to promote FtsZ polymerization and inhibit GTPase activity of FtsZ. Thus, FtsZ-IN-6 inhibits bacterial division to lead to death of bacterial cells. FtsZ-IN-6 shows bactericidal activity with no significant tendency to trigger bacterial resistance as well as rapid bactericidal properties. And FtsZ-IN-6 shows low hemolytic activity and cytotoxicity to mammalian cells[1].
Web ID
– HY-149224
Shipping
– Room temperature
Molecular Formula
– C28H22BrN3O2
References
– [1]Qiu H, et al. Design and synthesis of fascaplysin derivatives as inhibitors of FtsZ with potent antibacterial activity and mechanistic study. Eur J Med Chem. 2023 Jun 5;254:115348.
Molecular Weight
– 512.40
SMILES
– CC(C1=CC=CC(NC(C2=CC3=C(NC4=C3C=C[N+]5=C4C(C6=C5C=CC=C6)=O)C=C2)=O)=C1)C.[Br-]
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
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