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Products Details
Product Description
– FRM-024 is a potent CNS-penetrant gamma secretase modulator for familial Alzheimer’s disease.
Web ID
– HY-115726
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C22H22ClN5O2
References
– [1]Bursavich MG, et al. Discovery of the Oxadiazine FRM-024: A Potent CNS-Penetrant Gamma Secretase Modulator. J Med Chem. 2021 Oct 14;64(19):14426-14447.
CAS Number
– 2085780-87-4
Molecular Weight
– 423.90
SMILES
– CC1=CN(C2=C(OC)N=C(C3=NO[C@@H](C4CC4)[C@@H](C5=CC=C(Cl)C=C5)N3)C=C2)C=N1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– γ-secretase
Pathway
– Neuronal Signaling;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
