FRAX597

SKU HY-15542A-10 mg Category Tags , ,

$100$860

Products Details

Product Description

– FRAX597 is a potent group I p21-activated Kinases (PAKs) inhibitor with IC50 of 8, 13 and 19 nM for PAK1, 2 and 3.

Web ID

– HY-15542A

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C29H28ClN7OS

References

– [1]Licciulli S, et al. FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas. J Biol Chem. 2013 Oct 4;288(40):29105-14.

CAS Number

– 1286739-19-2

Molecular Weight

– 558.10

Compound Purity

– 99.79

SMILES

– O=C1C(C2=CC=C(C3=CN=CS3)C=C2Cl)=CC4=CN=C(NC5=CC=C(N6CCN(C)CC6)C=C5)N=C4N1CC

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 14.29 mg/mL (ultrasonic)

Target

– PAK

Isoform

– PAK1;PAK2;PAK3

Pathway

– Cell Cycle/DNA Damage;Cytoskeleton

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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