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Products Details
Product Description
– FR 113680 is a tripeptide substance P antagonist that interacts selectively with the NK1 neurokinin receptor[1].
Web ID
– HY-105436
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C35H39N5O6
References
– [1]Morimoto H, et al. FR 113680: a novel tripeptide substance P antagonist with NK1 receptor selectivity. Br J Pharmacol. 1992 May;106(1):123-6.|[2]Morimoto H, et al. Effects of FR 113680 and FK 224, novel tachykinin receptor antagonists, on cigarette smoke-induced rat tracheal plasma extravasation. Eur J Pharmacol. 1992 Nov 24;224(1):1-5.
CAS Number
– 126088-92-4
Molecular Weight
– 625.71
SMILES
– CN(CC1=CC=CC=C1)C([C@H](CC2=CC=CC=C2)NC([C@H](NC([C@H]([C@H](O)C)NC(C)=O)=O)CC3=CN(C=O)C4=C3C=CC=C4)=O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Neurokinin Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
