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Products Details
Product Description
– FRα-IN-1 (Compound 4) is a tumor-targeting agent. FRα-IN-1 shows selective anticancer activity towards folate receptors (FRα and FRβ) expression cells[1].
Web ID
– HY-147699
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H24N6O6
References
– [1]Golani LK, et al. Design, synthesis and biological evaluation of novel pyrrolo[2,3-d]pyrimidine as tumor-targeting agents with selectivity for tumor uptake by high affinity folate receptors over the reduced folate carrier. Bioorg Med Chem. 2020 Jun 15;28(12):115544.
CAS Number
– 2028296-64-0
Molecular Weight
– 456.45
SMILES
– O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(NCCCC(N2)=CC3=C2N=C(N)NC3=O)C=C1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Antifolate
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
