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Products Details
Product Description
– FRα-IN-1 (Compound 4) is a tumor-targeting agent. FRα-IN-1 shows selective anticancer activity towards folate receptors (FRα and FRβ) expression cells[1].
Web ID
– HY-147699
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H24N6O6
References
– [1]Golani LK, et al. Design, synthesis and biological evaluation of novel pyrrolo[2,3-d]pyrimidine as tumor-targeting agents with selectivity for tumor uptake by high affinity folate receptors over the reduced folate carrier. Bioorg Med Chem. 2020 Jun 15;28(12):115544.
CAS Number
– 2028296-64-0
Molecular Weight
– 456.45
SMILES
– O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(NCCCC(N2)=CC3=C2N=C(N)NC3=O)C=C1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Antifolate
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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