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Products Details
Product Description
– FPR1 antagonist 2 (compound 25b) is a formyl peptide receptor 1 (FPR1) antagonist with an IC50 of 70 nM. FPR1 antagonist 2 inhibits cell growth through a combined effect on cell proliferation and apoptosis and reduces cell migration, while inducing an increase in angiogenesis[1].
Web ID
– HY-156294
Shipping
– Room temperature
Molecular Formula
– C25H25F3O5
References
– [1]Fabio Francavilla, et al. Development of potent isoflavone-based formyl peptide receptor 1 (FPR1) antagonists and their effects in gastric cancer cell models. Eur J Med Chem. 2023 Oct 4:261:115854.
Molecular Weight
– 462.46
SMILES
– CC(OC1=CC2=C(C=C1CCCCCC)C(C(C3=CC=CC(OC)=C3)=C(C(F)(F)F)O2)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Formyl Peptide Receptor (FPR)
Pathway
– Apoptosis;GPCR/G Protein
Product type
– Reference compound
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