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FPL-55712 (free base)

Products Details

Product Description

– FPL-55712 free base is a leukotriene receptor antagonist. FPL-55712 free base is also an antagonist of slow reacting substance of anaphylaxis (SRS-A). FPL-55712 free base inhibits leukotriene-induced bronchoconstriction[1][2][3].

Web ID

– HY-107607

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C27H30O9

References

– [1]Folkerts G, Vet al. Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition. Eur J Pharmacol. 1995 Oct 16;285(2):R1-2.|[2]Chand N. FPL 55712 — an antagonist of slow reacting substance of anaphylaxis (SRS-A): a review. Agents Actions. 1979 Jun;9(2):133-40.|[3]O’Donnell M, et al. Pharmacologic properties of FPL 55712 administered by aerosol. Agents Actions. 1984 Jan;14(1):43-8.

CAS Number

– 40785-97-5

Molecular Weight

– 498.52

SMILES

– O=C(C(OC1=C(CCC)C(OCC(COC2=CC=C(C(O)=C2CCC)C(C)=O)O)=CC=C13)=CC3=O)O

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Leukotriene Receptor

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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