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Products Details
Product Description
– FPI-1465 acts a dual inhibitor of serine-β-Lactamases and Penicillin-binding proteins (PBPs).FPI-1465 inhibits PBP2 (IC50=1.0 µg/mL). FPI-1465 exhibits activity against β-lactamase CTX-M-15 and OXA-48 with Kds of 0.011 and 5.3 µM, respectively[1].
Web ID
– HY-139744
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C11H18N4O7S
References
– [1]Andrew M King, et al. Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins. ACS Chem Biol. 2016 Apr 15;11(4):864-8.
CAS Number
– 1452458-70-6
Molecular Weight
– 350.35
SMILES
– O=C([C@H]1[N@@]2C(N([C@H](CC1)C2)OS(=O)(O)=O)=O)NO[C@@H]3CCNC3
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
