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Fosinopril (sodium)
SKU
HY-B0382-100 mg
Category Reference compound
Tags Angiotensin-converting Enzyme (ACE);Apoptosis, Apoptosis;Metabolic Enzyme/Protease, Cardiovascular Disease
$139 – $185
Products Details
Product Description
– Fosinopril Sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.
Web ID
– HY-B0382
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C30H45NNaO7P
References
– [1]Ondetti, M.A., Structural relationships of angiotensin converting-enzyme inhibitors to pharmacologic activity. Circulation, 1988. 77(6 Pt 2): p. I74-8.|[2]Piepho, R.W., Overview of the angiotensin-converting-enzyme inhibitors. Am J Health Syst Pharm, 2000. 57 Suppl 1: p. S3-7.|[3]Sharma, S., et al., The hemodynamic effects of long-term ACE inhibition with fosinopril in patients with heart failure. Fosinopril Hemodynamics Study Group. Am J Ther, 1999. 6(4): p. 181-9.
CAS Number
– 88889-14-9
Molecular Weight
– 585.64
Compound Purity
– 99.89
SMILES
– O=C(O[Na])[C@H]1N(C(C[P@@](CCCCC2=CC=CC=C2)(O[C@H](OC(CC)=O)C(C)C)=O)=O)C[C@H](C3CCCCC3)C1
Clinical Information
– Launched
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 1.43 mg/mL (ultrasonic)|Ethanol : 16.67 mg/mL (ultrasonic)|H2O : 25 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Angiotensin-converting Enzyme (ACE);Apoptosis
Pathway
– Apoptosis;Metabolic Enzyme/Protease
Product type
– Reference compound
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