Products Details

Product Description

– Fomivirsen (ISIS-2922 free base) is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen is an antiviral agent that is used CMV research, incluiding in AIDs. Fomivirsen binds to and degrades the mRNAs encoding CMV immediate-early 2 protein, thus inhibiting virus proliferation[1][2].

Web ID

– HY-112958

Shipping

– Room temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C204H263N63O114P20S20

References

– [1]M D de Smet, et al. Fomivirsen- a phosphorothioate oligonucleotide for the treatment of CMV retinitis. Ocul Immunol Inflamm. 1999 Dec;7(3-4):189-98. |[2]Anna Kilanowska, et al. In vivo and in vitro studies of antisense oligonucleotides – a review. (Review Article) RSC Adv., 2020, 10, 34501-34516.

CAS Number

– 144245-52-3

Molecular Weight

– 6682.40

SMILES

– [Fomivirsen]

Clinical Information

– Launched

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– CMV

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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