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FN-439 (TFA)
$270 – $420
Products Details
Product Description
– FN-439 TFA is a selective collagenase-1 inhibitor. FN-439 TFA inhibits collagenase-1 with an IC50 value of 1 μM. FN-439 TFA can be used for the research of cancer and inflammation[1][2].
Web ID
– HY-100210A
Storage Temperature
– -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Molecular Formula
– C25H35F3N6O8
References
– [1]U Benbow, et al. Human breast cancer cells activate procollagenase-1 and invade type I collagen: invasion is inhibited by all-trans retinoic acid. Clin Exp Metastasis. 1999 May;17(3):231-8.|[2]H Anan, et al. Effects of a combination of an antibacterial agent (ofloxacin) and a collagenase inhibitor (FN-439) on the healing of rat periapical lesions. J Endod. 1996 Dec;22(12):668-73.
Molecular Weight
– 604.58
Compound Purity
– 99.61
SMILES
– OC(C(F)(F)F)=O.ONC([C@@H](C)NC([C@@H](CC(C)C)NC([C@H]1N(CCC1)C(CNC(C2=CC=C(C=C2)N)=O)=O)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– H2O : 250 mg/mL (ultrasonic)
Target
– MMP
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
