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Fmoc-Phe-Lys(Boc)-PAB
SKU
HY-139353-Get quote
Category ADC Related
Tags ADC Linker, Antibody-drug Conjugate/ADC Related, Cancer
Products Details
Product Description
– Fmoc-Phe-Lys(Boc)-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Web ID
– HY-139353
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C42H48N4O7
References
– [1]Raymond Firestone, et al. Hydrolyzable prodrugs for delivery of anticancer drugs to metastatic cells. WO1998013059A1.
CAS Number
– 206133-42-8
Molecular Weight
– 720.85
SMILES
– OCC(C=C1)=CC=C1NC([C@H](CCCCNC(OC(C)(C)C)=O)NC([C@H](CC2=CC=CC=C2)NC(OCC3C4=CC=CC=C4C5=CC=CC=C53)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Isoform
– Protease Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.