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Fmoc-L-Lys(N3-Aca-DIM)-OH
SKU
HY-151787-Get quote
Category Reference compound
Tags ADC Linker, Antibody-drug Conjugate/ADC Related, Others
Products Details
Product Description
– Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution[1].
Web ID
– HY-151787
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C35H43N5O6
References
– [1]Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.
CAS Number
– 2408993-39-3
Molecular Weight
– 629.75
SMILES
– [N-]=[N+]=NCCCCC/C(NCCCC[C@@H](C(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=C4C(CC(C)(CC/4=O)C)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.