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Fmoc-L-Dap(Pentynoyl)-OH
SKU
HY-151780-Get quote
Category Reference compound
Tags ADC Linker, Antibody-drug Conjugate/ADC Related, Others
Products Details
Product Description
– Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Dap(Pentynoyl)-OH serves as an amino acid building block for introducing alkyne functions into peptide sequences by standard Fmoc/tBu protocols. The alkyne residue can be engaged for copper catalyzed click reaction with organic azides or with tetrazines for copper-free conjugations[1]. Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-151780
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H22N2O5
References
– [1]Le Chevalier Isaad A, et al. Side chain-to-side chain cyclization by click reaction. J Pept Sci. 2009 Jul;15(7):451-4.
CAS Number
– 2250436-47-4
Molecular Weight
– 406.43
SMILES
– C#CCCC(NC[C@@H](C(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.