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Products Details
Product Description
– Fmoc-3VVD-OH (GMP) is GMP grade Fmoc-3VVD-OH (HY-78921). Fmoc-3VVD-OH is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
Web ID
– HY-78921AG
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C36H51N3O7
References
– [1]Michinori Akaiwa, et al. Synthesis and Evaluation of Linear and Macrocyclic Dolastatin 10 Analogues Containing Pyrrolidine Ring Modifications. ACS Omega. 2018 May 31;3(5):5212-5221.
CAS Number
– 863971-44-2
Molecular Weight
– 637.81
SMILES
– CN([C@H]([C@H](OC)CC(O)=O)[C@@H](C)CC)C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C)=O)=O
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
