Fluoflavine

$187$290

Products Details

Product Description

– Fluoflavine (ML-090) is a selective NOX1 inhibitor with an IC50 of 90 nM. Fluoflavine has >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50>10 μM). ML-090 has an IC50 of 360 nM in HEK293 cells[1].

Web ID

– HY-126195

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C14H10N4

References

– [1]SJ Brown, et al. Probe Report for NOX1 Inhibitors.

CAS Number

– 531-46-4

Molecular Weight

– 234.26

Compound Purity

– 99.41

SMILES

– C1(N2)=NC3=C(C=CC=C3)NC1=NC4=C2C=CC=C4

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– NADPH Oxidase

Isoform

– NOX1

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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