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FLT3-IN-17
$142 – $1,600
Products Details
Product Description
– FLT3-IN-17 inhibits CYPs and FLT3 mutants activity (IC50s: <0.5 nM for D835Y). FLT3-IN-17 is also a FAK inhibitor, with an IC50 value of 12 nM. FLT3 ligand-2 can be used in the research of cancers[1].
Web ID
– HY-148070
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H24N6O2S2
References
– [1]Hanna Cho, et al. Identification of Thieno[3,2- d]pyrimidine Derivatives as Dual Inhibitors of Focal Adhesion Kinase and FMS-like Tyrosine Kinase 3. J Med Chem. 2021 Aug 26;64(16):11934-11957.
CAS Number
– 2758999-62-9
Molecular Weight
– 480.61
Compound Purity
– 99.56
SMILES
– O=S(NC1=CC=CC(C2=CSC3=C2N=C(NC4=CC=C(N5CCNCC5)C=C4)N=C3)=C1)(C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 7.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Cytochrome P450;FAK;FLT3
Pathway
– Metabolic Enzyme/Protease;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
