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Products Details
Product Description
– Flt-3 Inhibitor III is a potent and selective FLT3 kinase inhibitor with an 50 of 50 nM. Flt-3 Inhibitor III shows less active against other kinases. Flt-3 Inhibitor III has anticancer effects[1].
Web ID
– HY-112475
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C21H23N3OS
References
– [1]Pascal Furet, et al. Aromatic interactions with phenylalanine 691 and cysteine 828: a concept for FMS-like tyrosine kinase-3 inhibition. Application to the discovery of a new class of potential antileukemia agents. J Med Chem. 2006 Jul 27;49(15):4451-4.
CAS Number
– 852045-46-6
Molecular Weight
– 365.49
SMILES
– C1(NC2=CC=C(OCCN3CCCC3)C=C2)=NC=C(C4=CC=CC=C4)S1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– FLT3;Tie
Isoform
– Tie2
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
