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Flovagatran

Products Details

Product Description

– Flovagatran (TGN 255) is a potent and reversible thrombin inhibitor (Ki: 9 nM). Flovagatran can be used in the research of arterial and venous thrombosis[1].

Web ID

– HY-10270

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C27H36BN3O7

References

– [1]Nelson DA, et al. Pharmacodynamic and efficacy profile of TGN 255, a novel direct thrombin inhibitor, in canine cardiopulmonary bypass and simulated mitral valve repair. J Extra Corpor Technol. 2008 Jun;40(2):116-22.

CAS Number

– 871576-03-3

Molecular Weight

– 525.40

SMILES

– O=C(OCC1=CC=CC=C1)N[C@H](CC2=CC=CC=C2)C(N3CCC[C@H]3C(N[C@@H](CCCOC)B(O)O)=O)=O

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– Thrombin

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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