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FLDP-5
SKU
HY-150791-Get quote
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB, DNA/RNA Synthesis;Reactive Oxygen Species
Products Details
Product Description
– FLDP-5 is a blood-brain barrier (BBB) penetrant curcuminoid analogues. FLDP-5 can induce production of ROS (Reactive Oxygen Species), DNA damage and cell cycle S phase arrest. FLDP-5 exhibits highly potent tumour-suppressive effects with anti-proliferative and anti-migratory activities on LN-18 cells[1].
Web ID
– HY-150791
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H21NO5
References
– [1]Razali NSC, et al. Curcumin piperidone derivatives induce anti-proliferative and anti-migratory effects in LN-18 human glioblastoma cells. Sci Rep. 2022 Jul 30;12(1):13131.
CAS Number
– 950665-12-0
Molecular Weight
– 367.40
SMILES
– O=C1/C(CNC/C1=CC2=CC=C(O)C(OC)=C2)=C/C3=CC=C(O)C(OC)=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis;Reactive Oxygen Species
Pathway
– Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
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