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Flavoxate-d4 (hydrochloride)
SKU
HY-B0549AS-1 mg
Category Isotope-Labeled Compounds
Tags GPCR/G Protein;Neuronal Signaling;Others, Isotope-Labeled Compounds;mAChR, Neurological Disease
Products Details
Product Description
– Flavoxate-d4 (hydrochloride) (Rec-7-0040-d4) is the deuterium labeled Flavoxate hydrochloride. Flavoxate Hydrochloride is a muscarinic AChR antagonist used in various urinary syndromes and as an antispasmodic[1][2].
Web ID
– HY-B0549AS
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C24H22D4ClNO4
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Kimura, Y., et al., Mechanisms of the suppression of the bladder activity by flavoxate. Int J Urol, 1996. 3(3): p. 218-27.|[3]Oka, M., et al., Brain pertussis toxin-sensitive G proteins are involved in the flavoxate hydrochloride-induced suppression of the micturition reflex in rats. Brain Res, 1996. 727(1-2): p. 91-8.|[4]Dansette, P.M.,et al. HMG-CoA reductase activity in human liver microsomes: comparative inhibition by statins. Exp Toxicol Pathol, 2000. 52(2): p. 145-8.
CAS Number
– 1189678-43-0
Molecular Weight
– 431.95
SMILES
– C(OC(C(N1CCCCC1)([2H])[2H])([2H])[2H])(=O)C2=C3C(C(=O)C(C)=C(O3)C4=CC=CC=C4)=CC=C2.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Isotope-Labeled Compounds;mAChR
Pathway
– GPCR/G Protein;Neuronal Signaling;Others
Product type
– Isotope-Labeled Compounds
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