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Products Details
Product Description
– FKBP51F67V-selective antagonist Ligand2 (example 3-3) is a potent FKBP51 F67V-selective antagonist ligand. FKBP51F67V-selective antagonist Ligand2 reverses the anxiogenic phenotype induced by overexpression of FKBP51 F67V in the amygdala. FKBP51F67V-selective antagonist Ligand2 binds to FKBP51 F67V, but not to wild-type FKBP51 or FKBP52[1].
Web ID
– HY-153990
Shipping
– Room temperature
Molecular Formula
– C43H56N2O10
References
– [1]Steffen GAALI, et al. Selective fkbp51 ligands for treatment of psychiatric disorders. Patent, WO2015039758A1.
CAS Number
– 1680228-76-5
Molecular Weight
– 760.91
SMILES
– O=C(N1[C@@H](CCCC1)C(O[C@@H](C2=CC(OCCN3CCOCC3)=CC=C2)CCC4=CC(OC)=C(C=C4)OC)=O)[C@H](C5=CC(OC)=C(C(OC)=C5)OC)CC=C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– FKBP
Pathway
– Apoptosis;Autophagy;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
