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FK-448 Free base

Products Details

Product Description

– FK-448 Free base is an effective and specific inhibitor of chymotrypsin, with an IC50 of 720 nM.

Web ID

– HY-100193

Shipping

– Room temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C25H30N2O3

References

– [1]Fujii S, et al. New synthetic inhibitors of chymotrypsin. J Biochem. 1984 Feb;95(2):319-22.|[2]Fujii S, et al. Promoting effect of the new chymotrypsin inhibitor FK-448 on the intestinal absorption of insulin in rats and dogs. J Pharm Pharmacol. 1985 Aug;37(8):545-9.

CAS Number

– 85858-76-0

Molecular Weight

– 406.52

SMILES

– O=C(C1CCCC2=C1C=CC=C2)OC3=CC=C(C(N4CCN(C(C)C)CC4)=O)C=C3

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Proteasome

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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