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FITC-labeled Tominersen
$650 – $2,500
Products Details
Product Description
– FITC-labeled Tominersen is Tominersen labeled with FITC. Tominersen (RG6042) is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen improves survival and reduces brain atrophy in mice. Tominersen can be used for the research of Huntington’s disease (HD).
Web ID
– HY-150236
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– N/A
References
– [1]Tabrizi SJ, et, al. Targeting Huntingtin Expression in Patients with Huntington’s Disease. N Engl J Med. 2019 Jun 13;380(24):2307-2316.|[2]Kordasiewicz HB, et al. Sustained therapeutic reversal of Huntington’s disease by transient repression of huntingtin synthesis. Neuron. 2012 Jun 21;74(6):1031-44.
Molecular Weight
– 7654.00
Compound Purity
– 95.72
SMILES
– [FITC-labeled Tominersen]
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– H2O : ≥ 100 mg/mL
Target
– Huntingtin
Pathway
– Neuronal Signaling
Product type
– Dye Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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