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Products Details
Product Description
– FHND5071 is a potent and selective RET kinase inhibitor, FHND5071 can exert antitumor effects by inhibiting RET autophosphorylation. FHND5071 can be used for tumor diseases research[1].
Web ID
– HY-149413
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C30H30D3N9O
References
– [1]Han Y, et al. Preclinical Pharmacokinetics and in vitro Metabolism of FHND5071, a Novel Selective RET Kinase Inhibitor. Eur J Drug Metab Pharmacokinet. 2023 Sep;48(5):595-614.
CAS Number
– 2761152-16-1
Molecular Weight
– 538.66
SMILES
– N#CC1=C2C(C3=CC=C(N4CC(C5)N(CC6=CC=C(OC)N=C6)C5C4)N=C3)=CC(N7CCN(C([2H])([2H])[2H])CC7)=CN2N=C1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– RET
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
