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FFN511
$426 – $682
Products Details
Product Description
– FFN511 is a potent fluorescent false neurotransmitters (FFNs) that targets neuronal vesicular monoamine transporter 2 (VMA T2). FFN511 inhibits serotonin binding to VMA T2-containing membranes with an IC50 of 1 µM. FFN511 directly images the dynamics of release during exocytosis, can be used to label dopamine terminals in live cortical-striatalacute slices[1][2].
Web ID
– HY-103465
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C17H20N2O2
References
– [1]Gubernator NG, et al. Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals. Science. 2009 Jun 12;324(5933):1441-4.|[2]Keighron JD, et al. Analytical tools to monitor exocytosis: a focus on new fluorescent probes and methods. Analyst. 2012 Apr 21;137(8):1755-63.
CAS Number
– 1004548-96-2
Molecular Weight
– 284.35
SMILES
– O=C1C=C(CCN)C2=CC3=C4N(CCC3)CCCC4=C2O1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Monoamine Transporter
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
