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Products Details
Product Description
– Fenoverine-d8 is the deuterium labeled Fenoverine[1]. Fenoverine (Spasmopriv) is an antispasmodic agent and inhibits calcium channel currents[2]. Fenoverine induces rhabdomyolysis[3].
Web ID
– HY-107349S
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C26H17D8N3O3S
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]J Mironneau, et al. Fenoverine inhibition of calcium channel currents in single smooth muscle cells from rat portal vein and myometrium. Br J Pharmacol. 1991 Sep;104(1):65-70. |[3]Chung-Wen Chen, et al. Rhabdomyolysis induced by fenoverine: a case report and literature review. Acta Neurol Taiwan. 2005 Sep14(3):143-6.
Molecular Weight
– 467.61
SMILES
– O=C(N1C2=C(C=CC=C2)SC3=CC=CC=C13)CN4C([2H])([2H])C([2H])([2H])N(CC5=CC=C(OCO6)C6=C5)C([2H])([2H])C4([2H])[2H]
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Calcium Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Isotope-Labeled Compounds
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