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Fazamorexant
$350 – $4,150
Products Details
Product Description
– Fazamorexant (YZJ-1139) is a potent orexin receptor antagonist. Fazamorexant can be used for insomnia research[1][2].
Web ID
– HY-152843
Storage Temperature
– 4°C (Powder, protect from light, stored under nitrogen)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C25H25FN4O2
References
– [1]Zhang Y, et al. Asymmetric Synthesis of Nortropanes via Rh-Catalyzed Allylic Arylation. ACS Catal. 2022 Aug 5;12(15):8995-9002.|[2]Zhenya Zeng, et al. Development of a Scalable Route with Efficient Stereoisomer Control to YZJ-1139, an Orexin Receptor Antagonist. Org. Process Res. Dev. 2022, 26, 2, 447-457.
CAS Number
– 1808918-69-5
Molecular Weight
– 432.49
Compound Purity
– 99.73
SMILES
– O=C(C1=C(C2=NC=CC=N2)C=CC(C)=C1)N3[C@]4([H])[C@@H](CC[C@@]3([H])CC4)COC5=CC=C(C=N5)F
Clinical Information
– Phase 3
Research Area
– Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Orexin Receptor (OX Receptor)
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
