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Falcarindiol
$370 – $600
Products Details
Product Description
– Falcarindiol, an orally active polyacetylenic oxylipin, activates PPARγ and increases the expression of the cholesterol transporter ABCA1 in cells. Falcarindiol induces apoptosis and autophagy. Falcarindiol has anti-inflammatory, antifungal, anticancer and antidiabetic properties[1][2]. Falcarindiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-N0364
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C17H24O2
References
– [1]Tingting Lu, et al. Autophagy contributes to falcarindiol-induced cell death in breast cancer cells with enhanced endoplasmic reticulum stress. PLoS One. 2017 Apr 25;12(4):e0176348.|[2]Camilla Bertel Andersen, et al. Falcarindiol Purified From Carrots Leads to Elevated Levels of Lipid Droplets and Upregulation of Peroxisome Proliferator-Activated Receptor-γ Gene Expression in Cellular Models. Front Pharmacol. 2020 Aug 28;11:565524.
CAS Number
– 55297-87-5
Molecular Weight
– 260.37
Compound Purity
– 99.48
SMILES
– C=C[C@H](O)C#CC#C[C@@H](O)/C=CCCCCCCC
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection; Metabolic Disease; Inflammation/Immunology
Solubility
– DMSO : ≥ 33.33 mg/mL
Target
– Apoptosis;Autophagy;PPAR
Isoform
– PPARγ
Pathway
– Apoptosis;Autophagy;Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
