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Products Details
Product Description
– F3226-1387 is a potent Entamoeba histolytica O-acetylserine sulfhydrylase EhOASS3 inhibitor with an IC50 value of 38 μM. F3226-1387 can suppress the growth of the amoeba[1].
Web ID
– HY-N10471
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H15ClN2O5
References
– [1]Dharavath S, et al. Crystal structure of O-Acetylserine sulfhydralase (OASS) isoform 3 from Entamoeba histolytica: Pharmacophore-based virtual screening and validation of novel inhibitors. Eur J Med Chem. 2020 Apr 15;192:112157.
CAS Number
– 618877-25-1
Molecular Weight
– 434.83
SMILES
– O=C1N(C2=NOC(C)=C2)C(C3=CC=CC(Cl)=C3)C(C(C4=CC5=CC=CC=C5O4)=O)=C1O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite;Parasite
Isoform
– Amebae
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
