Products Details

Product Description

– F 13714 (F 14679) is a prototypical 5-HT1A agonist with a pKi of 10.23. F 13714 induces large Ca2+ responses[1].

Web ID

– HY-146232

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C21H25ClF2N4O

References

– [1]Pauwels PJ, et al. Ca2+ responses in Chinese hamster ovary-K1 cells demonstrate an atypical pattern of ligand-induced 5-HT1A receptor activation. J Pharmacol Exp Ther. 2003 Nov;307(2):608-14.

CAS Number

– 208109-38-0

Molecular Weight

– 422.90

SMILES

– O=C(C1=CC(Cl)=C(F)C=C1)N2CCC(CNCC3=CC=C(C)C(NC)=N3)(F)CC2

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– 10 mM in DMSO

Target

– 5-HT Receptor

Isoform

– 5-HT1 Receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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