Ezurpimtrostat (hydrochloride)

$450$4,500

Products Details

Product Description

– Ezurpimtrostat hydrochloride (compound 2-3) is a potent and orally active anti-fibrotic agent. Ezurpimtrostat hydrochloride reduces significantly the liver fibrosis in DEN (diethyl nitrosamine) cirrhotic rat model. Ezurpimtrostat hydrochloride can be used for the research of fibrosis, cancer, autophagy and cathepsins B (CTSB), L (CTSL) and D (CTSD) related diseases [1].

Web ID

– HY-137978A

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C25H32Cl2N4

References

– [1]Philippe Halfon, et al. Substituted 2,4 diamino-quinoline as new medicament for fibrosis, autophagy and cathepsins b (ctsb), l (ctsl) and d (ctsd) related diseases. EP3620164A1.

CAS Number

– 1914148-73-4

Molecular Weight

– 459.45

Compound Purity

– 98.29

SMILES

– CC(NC1CCN(C2=CC(NCC3=CC=C(Cl)C=C3)=NC4=CC=CC=C24)CC1)(C)C.[H]Cl

Clinical Information

– Phase 2

Research Area

– Cancer; Metabolic Disease; Inflammation/Immunology

Solubility

– DMSO : 8.33 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Others

Pathway

– Others

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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