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Products Details
Product Description
– EZH2-IN-5 is a potent EZH2 inhibitor with IC50 values of 1.52 nM and 4.07 nM for wild-type and mutant Tyr641 EZH2, respectively[1].
Web ID
– HY-141566
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H37BrN4O2
References
– [1]Richard Chesworth, et al. Substituted benzene compounds. WO2012142513A1
CAS Number
– 1403258-69-4
Molecular Weight
– 517.50
SMILES
– CCN([C@H]1CC[C@@H](CC1)N(C)C)C2=C(C(C(NCC3=C(C=C(NC3=O)C)C)=O)=CC(Br)=C2)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Methyltransferase
Isoform
– EZH2
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
