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Products Details
Product Description
– EV-A71-IN-1 is a human enterovirus A71 (EV-A71) capsid protein inhibitor with an EC50 of 0.27 μM against EV-A71. EV-A71-IN-1 is a capsid binder that blocks the interaction between the viral VP1 and the host receptor hSCARB2. EV-A71-IN-1 inhibits a series of different human enteroviruses without significant cytotoxicity (CC50>56.2 μM)[1].
Web ID
– HY-145850
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C21H15N5S
References
– [1]Xu Z, et al. Discovery of aminothiazole derivatives as novel human enterovirus A71 capsid protein inhibitors. Bioorg Chem. 2022;122:105683.
CAS Number
– 2413648-96-9
Molecular Weight
– 369.44
SMILES
– C1(C2=CC=C(C=C2)NC3=NC(C4=CN=C5N=CC=CN45)=CS3)=CC=CC=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Enterovirus
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
