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Eupatilin
SKU
HY-N0783-10 mg
Category Natural Products
Tags Autophagy;Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor, Autophagy;PPAR, Inflammation/Immunology; Neurological Disease; Cancer
$77 – $462
Products Details
Product Description
– Eupatilin, a lipophilic flavonoid isolated from Artemisia argyi Lévl. et Van., is a PPARα agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.
Web ID
– HY-N0783
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C18H16O7
References
– [1]Jung Y, et al. Eupatilin, an activator of PPARα, inhibits the development of oxazolone-induced atopic dermatitis symptoms in Balb/c mice. Biochem Biophys Res Commun. 2018 Feb 5;496(2):508-514.|[2]Jung Y, et al. Eupatilin with PPARα agonistic effects inhibits TNFα-induced MMP signaling in HaCaT cells. Biochem Biophys Res Commun. 2017 Nov 4;493(1):220-226.|[3]Du L, et al. Eupatilin prevents H2O2-induced oxidative stress and apoptosis in human retinal pigment epithelial cells. Biomed Pharmacother. 2017 Jan;85:136-140.
CAS Number
– 22368-21-4
Molecular Weight
– 344.32
Compound Purity
– 98.07
SMILES
– O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(O)=C(OC)C(O)=C13
Clinical Information
– Launched
Research Area
– Inflammation/Immunology; Neurological Disease; Cancer
Solubility
– DMSO : 33.33 mg/mL (ultrasonic)
Target
– Autophagy;PPAR
Isoform
– PPARα
Pathway
– Autophagy;Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.