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Products Details
Product Description
– ETP-47037 is a potent and inhibitor of PI3Kα isoform with an IC50 value of 0.99 nM. ETP-47037 also inhibits the PI3Kβ, PI3Kδ, and PI3Kγ isoforms, with IC50 values of 49.2, 7.13, and 49.1 nM, respectively. ETP-47037 has the potential for the research of chemical modulation of telomere protection[1].
Web ID
– HY-139810
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H27N9O3S
References
Р[1]M̩ndez-Pertuz M, et al. Modulation of telomere protection by the PI3K/AKT pathway. Nat Commun. 2017;8(1):1278.
CAS Number
– 1316760-76-5
Molecular Weight
– 473.55
SMILES
– O=S(N1CCN(CC1)CC2=NN3C=C(C4=CN=C(N)N=C4)N=C(N5CCOCC5)C3=C2)(C)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– PI3K
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
