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Ethoxzolamide
SKU
HY-B1480-100 mg
Category Reference compound
Tags Anti-infection;Metabolic Enzyme/Protease, Bacterial;Carbonic Anhydrase, Infection; Inflammation/Immunology
$170 – $187
Products Details
Product Description
– Ethoxzolamide is a carbonic anhydrase inhibitor with Ki of 1 nM.
Web ID
– HY-B1480
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C9H10N2O3S2
References
– [1]Maren TH, et al. Relations among IOP reduction, ocular disposition and pharmacology of the carbonic anhydrase inhibitor ethoxzolamide. Exp Eye Res. 1992 Jul;55(1):73-9.|[2]Benjamin K. Johnson, et al. The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits theMycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence. Antimicrob Agents Chemother. 2015 Aug; 59(8): 4436–4445.|[3]Song Gao, et al. Development and validation of an UPLC-MS/MS method for the quantification of ethoxzolamide in plasma and bioequivalent buffers: Applications to absorption, brain distribution, and pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Apr 1; 0: 54–59.
CAS Number
– 452-35-7
Molecular Weight
– 258.32
Compound Purity
– 99.43
SMILES
– O=S(C1=NC2=CC=C(OCC)C=C2S1)(N)=O
Clinical Information
– Launched
Research Area
– Infection; Inflammation/Immunology
Solubility
– DMSO : ≥ 100 mg/mL|H2O : 1 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– Bacterial;Carbonic Anhydrase
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.