Products Details

Product Description

– Estrone-13C2 is the 13C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

Web ID

– HY-B0234S3

Shipping

– Room temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C16 13C2H22O2

References

– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Caupos E, et al. Photodegradation of estrone enhanced by dissolved organic matter under simulated sunlight. Water Res. 2011;45(11):3341-3350.|[3]de Padua Mansur A, et al. Long-term prospective study of the influence of estrone levels on events in postmenopausal women with or at high risk for coronary artery disease. ScientificWorldJournal. 2012;2012:363595.

CAS Number

– 82938-06-5

Molecular Weight

– 272.35

SMILES

– C[C@]1([C@](CC2)([H])[C@]3([H])CCC4=C(C=C[13C](O)=[13CH]4)[C@@]3([H])CC1)C2=O

Clinical Information

– No Development Reported

Research Area

– Endocrinology; Cancer

Solubility

– 10 mM in DMSO

Target

– Endogenous Metabolite;Estrogen Receptor/ERR;Isotope-Labeled Compounds

Pathway

– Metabolic Enzyme/Protease;Others;Vitamin D Related/Nuclear Receptor

Product type

– Isotope-Labeled Compounds

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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