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Products Details
Product Description
– Estrone-13C2 is the 13C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].
Web ID
– HY-B0234S3
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C16 13C2H22O2
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Caupos E, et al. Photodegradation of estrone enhanced by dissolved organic matter under simulated sunlight. Water Res. 2011;45(11):3341-3350.|[3]de Padua Mansur A, et al. Long-term prospective study of the influence of estrone levels on events in postmenopausal women with or at high risk for coronary artery disease. ScientificWorldJournal. 2012;2012:363595.
CAS Number
– 82938-06-5
Molecular Weight
– 272.35
SMILES
– C[C@]1([C@](CC2)([H])[C@]3([H])CCC4=C(C=C[13C](O)=[13CH]4)[C@@]3([H])CC1)C2=O
Clinical Information
– No Development Reported
Research Area
– Endocrinology; Cancer
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite;Estrogen Receptor/ERR;Isotope-Labeled Compounds
Pathway
– Metabolic Enzyme/Protease;Others;Vitamin D Related/Nuclear Receptor
Product type
– Isotope-Labeled Compounds
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