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Products Details
Product Description
– Estrogen receptor-IN-1 (compound 16) is a potent estrogen receptor (ER) inhibitor with IC50s of 13, 5µM for ERα and Erβ, respectively[1].
Web ID
– HY-150601
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C14H16OSi
References
– [1]Saito H, et al. Phosphine boranes as less hydrophobic building blocks than alkanes and silanes: Structure-property relationship and estrogen-receptor-modulating potency of 4-phosphinophenol derivatives. Bioorg Med Chem. 2020 Feb 15;28(4):115310.
CAS Number
– 74027-99-9
Molecular Weight
– 228.36
SMILES
– OC1=CC=C([Si](C)(C)C2=CC=CC=C2)C=C1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Estrogen Receptor/ERR
Isoform
– ERα;ERβ
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
