Products Details

Product Description

– Estrogen receptor antagonist 7 (compound 13) is a potent estrogen receptors (ER) antagonist. Estrogen receptor antagonist 7 has antiproliferative activity against breast and ovarian cancer cells. Anticancer and anti-uterotrophic activities[1].

Web ID

– HY-143253

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C23H17N3O4

References

– [1]Ragab MA, et al. Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity. Bioorg Chem. 2022 Feb;119:105554.

CAS Number

– 2889371-04-2

Molecular Weight

– 399.40

SMILES

– OC(C=C1)=CC(CCC2=C3C4=CC=C(C=C4)O)=C1C2=NN3C5=CC=C([N+]([O-])=O)C=C5

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Estrogen Receptor/ERR

Pathway

– Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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